当前位置: X-MOL 学术Biomol. NMR Assign. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
1H, 13C and 15N resonance assignments for the tandem CUE domains from chromatin remodeler SMARCAD1.
Biomolecular NMR Assignments ( IF 0.9 ) Pub Date : 2019-03-27 , DOI: 10.1007/s12104-019-09888-9
Antonio J Biasutto 1, 2 , Philip M West 2 , Erika J Mancini 2, 3 , Christina Redfield 1
Affiliation  

SMARCAD1 is a non-canonical chromatin remodelling ATPase, unique in its domain organization in that is encodes tandem ubiquitin binding CUE domains along with a classical SNF2 helicase ATP-dependent motor. SMARCAD1 is conserved from yeast to humans and has reported roles in the maintenance of heterochromatin following replication and in double-strand break repair. Here we present the 1H, 13C and 15N assignments for the tandem CUE domains and for the disordered regions that flank them. These assignments provide the starting point for detailed investigations of the structure and interactions of this region of SMARCAD1.

中文翻译:

染色质重塑器SMARCAD1的串联CUE域的1H,13C和15N共振分配。

SMARCAD1是一种非规范的染色质重塑ATPase,在其域组织中是独特的,因为它编码串联泛素结合的CUE域以及经典的SNF2解旋酶ATP依赖性马达。SMARCAD1从酵母到人类都是保守的,并已报道了复制后异染色质的维持和双链断裂修复中的作用。在这里,我们给出了串联CUE域和位于其侧面的无序区域的1 H,13 C和15 N分配。这些任务为详细研究SMARCAD1该区域的结构和相互作用提供了起点。
更新日期:2019-03-27
down
wechat
bug