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Airway Clearance Management with Vaküm Technology in Subjects with Ineffective Cough: A Pilot Study on the Efficacy, Acceptability Evaluation, and Perception in Children with Cerebral Palsy.
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2019-09-12 , DOI: 10.1089/ped.2018.0933
Luca Bertelli 1 , Giulia Bardasi 1 , Salvatore Cazzato 2 , Emanuela Di Palmo 1 , Marcella Gallucci 1 , Giampaolo Ricci 1 , Andrea Pession 1
Affiliation  

Background: In the medical complexity of a children with cerebral palsy, impaired airway clearance represents a major problem, leading to significative respiratory morbidity and mortality. Its management is difficult because of limited cooperation and poor tolerance to invasive treatments. Free Aspire® (FA) is a device designed to remove bronchial secretions noninvasively, without generating cough. Methods: The aim of our pilot prospective study is to assess the efficacy and acceptability of FA in removing airway obstruction in subjects with cerebral palsy and ineffective cough. We enrolled 11 subjects. At enrollment and after 3, 6, and 12 months, we collected data regarding health care resources use for respiratory exacerbations, perceived efficacy, and acceptability of treatment. Results: We observed a reduction in emergency room (ER) accesses, home pharmacological treatment, hospitalizations number, and hospital stay length. In particular after 12 months we observed a reduction of 74% in ER accesses and home pharmacological treatment, 38% in hospitalizations number, and 17% in hospital stay length for respiratory exacerbations. The 100% of caregivers considered the treatment effective and simple to use and noted an improvement in subjects' general condition. They also reported good treatment tolerance of subjects, with an overall good compliance. Conclusion: The study demonstrates that FA is an effective device for the removal of bronchial secretions, with a positive caregivers' perception, that favored a good long-term compliance.

中文翻译:

使用Vaküm技术对咳嗽无效的患者进行气道清理管理:对脑瘫儿童的疗效,可接受性评估和知觉的初步研究。

背景:在脑瘫患儿的医疗复杂性中,气道清除功能障碍是一个主要问题,导致明显的呼吸道发病率和死亡率。由于合作有限且对侵入性治疗的耐受性差,因此难以对其进行管理。FreeAspire®(FA)是一种旨在无创地清除支气管分泌物而不会产生咳嗽的设备。方法:我们的前瞻性前瞻性研究的目的是评估FA清除脑瘫和无效咳嗽患者的气道阻塞的功效和可接受性。我们招收了11个科目。在入组时,3、6和12个月后,我们收集了有关呼吸急症的医疗保健资源使用,感知的疗效和治疗可接受性的数据。结果:我们观察到急诊室(ER)的访问减少了,家庭药物治疗,住院次数和住院时间。尤其是在12个月后,我们观察到急症发作和家庭药物治疗减少了74%,住院次数减少了38%,住院时间减少了17%。100%的护理人员认为该治疗有效且易于使用,并注意到受试者总体状况有所改善。他们还报告了受试者对治疗的耐受性良好,总体依从性良好。结论:研究表明,FA是一种有效的去除支气管分泌物的装置,具有积极的看护者感知能力,有利于长期良好的依从性。尤其是在12个月后,我们观察到急症发作和家庭药物治疗减少了74%,住院次数减少了38%,住院时间减少了17%。100%的护理人员认为该治疗有效且易于使用,并注意到受试者总体状况有所改善。他们还报告了受试者对治疗的耐受性良好,总体依从性良好。结论:研究表明,FA是一种有效的去除支气管分泌物的装置,具有积极的看护者感知能力,有利于长期良好的依从性。尤其是在12个月后,我们观察到急症发作和家庭药物治疗减少了74%,住院次数减少了38%,住院时间减少了17%。100%的护理人员认为该治疗有效且易于使用,并注意到受试者总体状况有所改善。他们还报告了受试者对治疗的耐受性良好,总体依从性良好。结论:研究表明,FA是一种有效的去除支气管分泌物的装置,具有积极的看护者感知能力,有利于长期良好的依从性。100%的护理人员认为该治疗有效且易于使用,并注意到受试者总体状况有所改善。他们还报告了受试者对治疗的耐受性良好,总体依从性良好。结论:研究表明,FA是一种有效的去除支气管分泌物的装置,具有积极的看护者感知能力,有利于长期良好的依从性。100%的护理人员认为该治疗有效且易于使用,并注意到受试者总体状况有所改善。他们还报告了受试者对治疗的耐受性良好,总体依从性良好。结论:研究表明,FA是一种有效的去除支气管分泌物的装置,具有积极的看护者感知能力,有利于长期良好的依从性。
更新日期:2019-11-01
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