Dementia with Lewy bodies is a progressive neurodegenerative disorder, clinically characterized by gradual cognitive impairment and fluctuating cognition, behavioral changes and recurrent visual hallucinations, and autonomic function and movement symptoms in the type of parkinsonism. It is the second most common type of dementia in the Western world after Alzheimer disease. Over the last 20 years, many neurophysiological, neuroimaging, and cerebrospinal fluid (CSF) biomarkers have been described toward a better discrimination between dementia with Lewy bodies, Alzheimer disease, and other neurodegenerative conditions.In the present review, we aim to describe the neurophysiological, imaging, and CSF biomarkers in dementia with Lewy bodies and to question whether they could be reliable tools for the clinical practice.

中文翻译：

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路易体痴呆患者的脑脊液，影像学和生理生物标志物。

路易氏体痴呆是一种进行性神经退行性疾病，临床特征是逐渐的认知障碍和认知波动，行为改变和反复出现幻觉，以及帕金森病类型的自主功能和运动症状。它是仅次于阿尔茨海默氏病的西方第二大痴呆类型。在过去的20年中，已经描述了许多神经生理学，神经影像学和脑脊髓液（CSF）生物标记物，以更好地区分路易氏体痴呆症，阿尔茨海默氏病和其他神经退行性疾病。 ，路易氏体痴呆患者的影像学，影像学和脑脊液生物标志物，并质疑它们是否可以作为临床实践的可靠工具。