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Association Between Individual Components of Metabolic Syndrome and Cognitive Function in Northeast Rural China.
American Journal of Alzheimer's Disease and other Dementias ( IF 3.4 ) Pub Date : 2019-07-28 , DOI: 10.1177/1533317519865428
Xue Wang 1 , Dechun Luan 2 , Shimeng Xin 1 , Yang Liu 1 , Qian Gao 1
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AIM The aim of this article was to examine associations between metabolic syndrome and its individual components with cognitive function among rural elderly population in northeast China. METHODS Our study included 1047 residents aged older than 60 years in a northeast rural area. All were interviewed and data were obtained including sociodemographic and medical histories. Cognitive function was assessed by Mini-Mental State Examination. Metabolic syndrome was defined by NCEP-ATP III. RESULTS After adjusted for confounding factors, metabolic syndrome was inversely associated with cognitive function (odds ratio [OR] = 1.79; 95% confidence interval [CI]: 1.06-3.01) especially in participants aged less than 70 years old (OR = 2.60; 95% CI: 1.27-5.26). In addition, participants with metabolic syndrome had worse language function, which is a part of cognitive function (OR = 2.64; 95% CI: 1.39-5.00). Individual metabolic syndrome components, especially abdominal obesity and hyperglycemia, had significant association with cognitive function (OR = 0.72, 95% CI: 0.56-0.92 and OR = 1.41; 95% CI: 1.12-1.78, respectively). CONCLUSIONS Abdominal obesity might be a protective factor for cognitive function. However, hyperglycemia might be a risk factor.
更新日期:2019-11-01
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