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Electroanalytical Approaches for Determination of Prostate Cancer Drugs in Biological Samples and Dosage Forms.
Critical Reviews in Analytical Chemistry ( IF 5 ) Pub Date : 2019-01-15 , DOI: 10.1080/10408347.2018.1538768
Cafer Saka 1
Affiliation  

Prostate cancer is the second most common malignant type of cancer in men and fifth among fatal types of cancer. Because drugs used in prostate cancer, such as in many other drugs, are also present in low concentrations in body fluids, it is important to develop highly sensitive and sensitive methods that allow the correct amount of prostate cancer drugs to be determined at low concentrations in biological specimens. Electrochemical approaches for the quantitation of prostate cancer drugs have several advantages over other common techniques, including sensitive, selective, fast, broad linear concentration range. Over the years, various modified working electrodes such as graphite, glassy carbon, carbon paste electrode, carbon composites, and nanotubes have been developed and used in various forms for electroanalytical determinations of prostate cancer drugs. One of the important developments in the electroanalytical chemistry is the surface modification of electrodes. The various sensing strategies for the electrochemical detection techniques such as voltammetry, polarography, amperometry, potentiometry have been used for prostate cancer drugs. This review focuses on studies published over the past years on sensitive and selective detection of prostate cancer drugs in biological fluids and dosage forms using electrochemical methods.

中文翻译:

用于确定生物样品和剂型中前列腺癌药物的电分析方法。

前列腺癌是男性第二大最常见的恶性肿瘤,在致命型癌症中排名第五。由于前列腺癌中使用的药物(例如许多其他药物)也以低浓度存在于体液中,因此开发出高度敏感的方法非常重要,这些方法应能够以较低的浓度确定正确量的前列腺癌药物。生物标本。定量前列腺癌药物的电化学方法相对于其他常用技术具有多种优势,包括灵敏,选择性,快速,宽线性浓度范围。多年来,各种改良的工作电极,例如石墨,玻璃碳,碳糊电极,碳复合材料,已经开发了纳米管和纳米管,并以各种形式用于前列腺癌药物的电分析测定。电分析化学的重要发展之一是电极的表面改性。用于电化学检测技术的各种传感策略,例如伏安法,极谱法,安培法,电位法,已用于前列腺癌药物。这篇综述的重点是过去几年发表的关于使用电化学方法灵敏和选择性地检测生物体液和剂型中前列腺癌药物的研究。电位计已用于前列腺癌药物。这篇综述的重点是过去几年发表的关于使用电化学方法灵敏和选择性地检测生物体液和剂型中前列腺癌药物的研究。电位计已用于前列腺癌药物。这篇综述的重点是过去几年发表的关于使用电化学方法灵敏和选择性地检测生物体液和剂型中前列腺癌药物的研究。
更新日期:2019-01-12
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