The aim of this study was to investigate the response of a tumor and parent vessels to stimulating factors in the tumor microenvironment in different configurations. How a tumor grows and induces angiogenesis in different distances of a parent vessel is investigated. Moreover, interstitial fluid pressure and its effects on tumor cell phenotype are considered in the model.

中文翻译：

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数学建模揭示了初始肿瘤的密度及其与亲代血管的距离如何改变血管肿瘤的生长趋势。

这项研究的目的是研究不同配置下肿瘤和亲代血管对肿瘤微环境中刺激因子的反应。研究了肿瘤如何在亲代血管的不同距离内生长并诱导血管生成。此外，模型中考虑了间质液压力及其对肿瘤细胞表型的影响。