The transport of peptides in microorganisms plays an important role in their physiology and behavior, both as a nutrient source and as a proxy to sense their environment. This latter function is evidenced in Gram-positive bacteria where cell-cell communication is mediated by small peptides. Here, we highlight the importance of the oligopeptide permease (Opp) systems in the various major processes controlled by signaling peptides, such as sporulation, virulence and conjugation. We underline that the functioning of these communication systems is tightly linked to the developmental status of the bacteria via the regulation of opp gene expression by transition phase regulators.

中文翻译：

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寡肽ABC导入剂是革兰氏阳性细菌中必不可少的沟通渠道。

肽在微生物中的运输在其生理和行为中起着重要的作用，既作为营养来源，又作为感知环境的代理。后一种功能在革兰氏阳性细菌中得到证实，该细菌中的细胞间通讯是由小肽介导的。在这里，我们强调了寡肽通透酶（Opp）系统在信号肽控制的各个主要过程中的重要性，例如孢子形成，毒力和结合。我们强调，这些通信系统的功能通过过渡相调节剂对opp基因表达的调节与细菌的发育状态紧密相关。