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Roles of FtsEX in cell division.
Research in Microbiology ( IF 2.6 ) Pub Date : 2019-08-01 , DOI: 10.1016/j.resmic.2019.07.003
Sebastien Pichoff 1 , Shishen Du 1 , Joe Lutkenhaus 1
Affiliation  

FtsEX is a member of a small subclass of ABC transporters that uses mechano-transmission to perform work in the periplasm. FtsEX controls periplasmic peptidoglycan (PG) hydrolase activities in many Gram negative and positive organisms to ensure the safe separation of daughter cells during division. In these organisms FtsEX localizes to the Z ring and uses its ATPase activity to regulate its periplasmic effectors. In Escherichia coli, FtsEX also participates in building the divisome and coordinates PG synthesis with PG hydrolysis. This review discusses studies that are beginning to elucidate the mechanisms of FtsEX's various roles in cell division.

中文翻译:

FtsEX在细胞分裂中的作用。

FtsEX是ABC转运蛋白一小类的成员,该转运蛋白使用机械传​​递在周质中进行工作。FtsEX控制许多革兰氏阴性和阳性生物中的周质肽聚糖(PG)水解酶活性,以确保分裂过程中子细胞的安全分离。在这些生物中,FtsEX定位于Z环并利用其ATPase活性来调节其周质效应子。在大肠埃希氏菌中,FtsEX还参与构建divisome,并通过PG水解来协调PG的合成。这篇评论讨论了开始阐明FtsEX在细胞分裂中各种作用机制的研究。
更新日期:2019-11-01
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