Background. Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a surgical treatment to reduce the “off” state motor symptoms of Parkinson’s disease (PD). Postural instability is one of the major impairments, which induces disabilities of activities of daily living (ADLs). The effectiveness of STN-DBS for postural instability is unclear, and the effect of rehabilitation following STN-DBS has remained uncertain. Objective. The purpose of this study was to examine changes in balance ability, gait function, motor performance, and ADLs following 2 weeks of postoperative rehabilitation in PD patients treated with STN-DBS. Methods. Sixteen patients were reviewed retrospectively from February 2016 to March 2017. All patients were tested in their “on” medication state for balance and gait performance using the Mini-Balance Evaluation Systems Test (Mini-BESTest) and the Timed “Up and Go” (TUG) test before the operation, after the operation, and during the discharge period. The UPDRS motor score (UPDRS-III) and Barthel Index (BI) were assessed before the operation and during the discharge period. Rehabilitation focused on muscle strengthening with stretching and proactive balance training. Friedman’s test and the post hoc Wilcoxon’s signed-rank test were used to analyze the balance assessments, and ANOVA and the post hoc Tukey’s test were used to analyze gait performance. The significance level was . Results. During the discharge period, the Mini-BESTest and TUG were significantly improved compared with the preoperative and postoperative periods (). There were no differences between preoperative and postoperative periods in the Mini-BESTest () and TUG (). The BI and motor sections of the UPDRS did not differ significantly between the preoperative and postoperative periods (, ). Conclusion. The results of this study suggest that postoperative rehabilitation improves balance and gait ability in patients with PD treated with STN-DBS.

中文翻译：

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丘脑底核深部脑刺激 (STN-DBS) 治疗帕金森病患者术后康复的平衡和步态改善。

背景。丘脑底核深部脑刺激 (STN-DBS) 是一种手术治疗，可减少帕金森病 (PD) 的“关闭”状态运动症状。姿势不稳是导致日常生活活动障碍 (ADLs) 的主要障碍之一。STN-DBS 对姿势不稳的有效性尚不清楚，STN-DBS 后的康复效果仍不确定。客观。本研究的目的是检查接受 STN-DBS 治疗的 PD 患者术后康复 2 周后平衡能力、步态功能、运动表现和 ADL 的变化。方法. 从 2016 年 2 月到 2017 年 3 月，对 16 名患者进行了回顾性审查。使用迷你平衡评估系统测试 (Mini-BESTest) 和定时“Up and Go”测试所有患者在“服用”药物状态下的平衡和步态表现。 TUG) 运行前、运行后和放电期间的测试。在手术前和出院期间评估UPDRS运动评分（UPDRS-III）和Barthel指数（BI）。康复的重点是通过伸展和主动平衡训练来加强肌肉。Friedman 检验和事后 Wilcoxon 符号秩检验用于分析平衡评估，ANOVA 和事后 Tukey 检验用于分析步态表现。显着性水平为。结果 . 出院期间Mini-BESTest和TUG均较术前、术后有明显改善（）。Mini-BESTest ( )和 TUG ( )在术前和术后期间没有差异。UPDRS 的 BI 和运动部分在术前和术后期间没有显着差异 ( , )。结论。本研究结果表明，术后康复改善了接受 STN-DBS 治疗的 PD 患者的平衡和步态能力。