A considerable increase in creatinine kinase (CK) activity and gastrin hormone due to exercise has been observed in sled dogs during endurance mushing races; however, there have been no studies on sled dogs during recreational mushing. Although oxytocin hormone is involved in social behaviors and empathy, it has not been studied in sled dogs. This study aimed to assess changes in plasma CK activity, and gastrin and oxytocin concentrations in adult sled dogs used in touristic mushing in North Patagonia, Argentina. Blood samples were collected before, during, and after the winter season of 2017. Creatinine kinase activity measurement was done using an enzymatic assay. Hormone analyses were performed using commercial Enzyme-Linked InmunoSorbent Assay kits. Results showed an expected two-fold increase in CK activity during the winter, with recovering basal values after winter (< 400 UI/L), low and stable levels of gastrin (9.4 ± 8.8 pg/mL), and a slight increase in oxytocin (23%) after mushing activities. No evidence indicated gastrin alterations or muscular damage from touristic mushing, but an oxytocin increase would indicate a stimulation of the brain reward system.

在耐力赛期间，雪橇犬观察到运动引起的肌酸酐激酶（CK）活性和胃泌素激素的显着增加；但是，还没有关于雪橇犬在娱乐性m草期间的研究。尽管催产素与社会行为和移情有关，但尚未在雪橇犬中进行研究。这项研究的目的是评估阿根廷北巴塔哥尼亚旅游m鼠使用的成年雪橇犬血浆CK活性以及胃泌素和催产素浓度的变化。在2017年冬季之前，之中和之后采集血液样本。肌酐激酶活性的测定采用酶法测定。使用商业酶联免疫吸附测定试剂盒进行激素分析。结果表明，冬季的CK活性有望提高两倍，冬季（<400 UI / L）后恢复基础值，胃泌素水平低而稳定（9.4±8.8 pg / mL），催吐作用后催产素略有增加（23％）。没有证据表明胃粘膜改变或旅游性ush缩引起的肌肉损害，但催产素的增加将表明大脑奖励系统受到刺激。