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Improvement of cognitive functions by oral intake of Hericium erinaceus.
Biomedical Research ( IF 1.2 ) Pub Date : 2019-01-01 , DOI: 10.2220/biomedres.40.125
Yuusuke Saitsu 1 , Akemi Nishide 2 , Kenji Kikushima 3 , Kuniyoshi Shimizu 4 , Koichiro Ohnuki 1
Affiliation  

Hericium erinaceus has been recognized as medical mushroom since ancient time, but its scientific evidence for human health has been still uncertain. In this study, we tested a randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the improvement of the cognitive functions by taking supplements containing fruiting body of H. erinaceus for 12 weeks. We performed three kinds of tests: Mini Mental State Examination (MMSE), Benton visual retention test, and Standard verbal paired-associate learning test (S-PA). MMSE alone showed that oral intake of H. erinaceus significantly improved cognitive functions and prevented from the deterioration. We speculate that various chemical compounds, including hericenones, in the mushroom have multiple effects to the brain neural networks and improve cognitive functions. Oral intake of H.erinaceus is safe and convenient method for dementia prevention so far.

中文翻译:

通过口服猴头菇来改善认知功能。

猴头菇自古以来就被认为是药用蘑菇,但其对人体健康的科学依据仍不确定。在这项研究中,我们测试了一项随机,双盲,安慰剂对照的平行组比较研究,以评估通过服用含有猴头菌子实体的补品12周来改善认知功能的方法。我们执行了三种测试:迷你心理状态测验(MMSE),本顿视力保持测验和标准言语配对联想学习测验(S-PA)。单独的MMSE表明,口服猴头菌能显着改善认知功能并防止其恶化。我们推测蘑菇中的各种化学物质(包括Hericenones)对大脑神经网络具有多种作用,并改善了认知功能。
更新日期:2019-11-01
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