Chlamydia pneumoniae is a ubiquitous pathogen causing disease in humans, mammals, birds, reptiles, and amphibians. Since 2012, C. pneumoniae infection has caused neurologic disease and mortality in a breeding colony of endangered Houston toads (Anaxyrus houstonensis) at the Houston Zoo. The purpose of this report is to present the histopathologic and ultrastructural characteristics of C. pneumoniae infection in Houston toads. Fourteen cases were evaluated by histopathology and 1 case was evaluated by electron microscopy. The major histopathologic finding was necrotizing and histiocytic polioencephalomyelitis and ganglionitis. Bacteria formed intracytoplasmic inclusions within neurons but frequently extended into the surrounding tissue from necrotic cells. Ultrastructural evaluation showed the bacteria formed reticulate and elementary bodies characteristic of Chlamydia spp.

中文翻译：

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休斯顿蟾蜍（Anaxyrus houstonensis）的肺炎衣原体脊髓灰质炎和神经节炎。

肺炎衣原体是一种普遍存在的病原体，在人类，哺乳动物，鸟类，爬行动物和两栖动物中引起疾病​​。自2012年以来，肺炎衣原体的感染已在休斯顿动物园的濒临灭绝的休斯顿蟾蜍繁殖种群（Anaxyrus houstonensis）中引起神经系统疾病和死亡。本报告的目的是介绍休斯顿蟾蜍肺炎衣原体感染的组织病理学和超微结构特征。通过组织病理学评估14例，通过电子显微镜评估1例。主要的组织病理学发现是坏死性和组织细胞性脊髓灰质炎和神经节炎。细菌在神经元内形成胞浆内包涵体，但经常从坏死细胞延伸到周围组织。