当前位置: X-MOL 学术Rev. Iberoam. Micol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Osteomyelitis of the rib cage by Aspergillus flavus.
Revista Iberoamericana de Micología ( IF 1.9 ) Pub Date : 2019-05-22 , DOI: 10.1016/j.riam.2019.02.002
María Fernanda Landaburu 1 , Gabriela López Daneri 2 , Federico Ploszaj 2 , Mariana Kruss 3 , Alejandra Vinante 3 , Cecilia H Veciño 2 , María Teresa Mujica 2
Affiliation  

Background

Aspergillus osteomyelitis of the ribs is relatively uncommon. It is a debilitating and severe form of invasive aspergillosis.

Case report

A 61year-old female presented with spontaneous chest pain on the right side of the rib cage and a palpable soft-tissue mass. FDG-PET/CT scan identified activity in the infected site. The lesion was punctured, and purulent material was sent to the laboratory. Aspergillus complex Flavi was isolated. An antifungal treatment with voriconazole was started. The lesion healed, and no recurrence was observed at 8-month follow-up. Molecular identification of the isolate was based on PCR amplification and sequencing of β-tubulin gene. Aspergillus flavus was identified.

Conclusions

Our case highlights the relevance of microbiological studies in patients with osteomyelitis and the involvement of soft tissue. The FDG-PET/CT scan was found to be a useful tool for revealing the extent of the disease and evaluating the response to the antifungal therapy.



中文翻译:

黄曲霉菌引起的肋骨骨髓炎。

背景

肋骨曲霉骨髓炎相对不常见。它是一种令人衰弱的严重形式的侵袭性曲霉病。

案例报告

一名61岁的女性在胸廓右侧出现自发性胸痛,并且可触知的软组织肿块。FDG-PET / CT扫描可确定感染部位的活性。穿刺病变,并将化脓性材料送至实验室。分离了曲霉复合物黄病毒。开始使用伏立康唑进行抗真菌治疗。病变已愈合,在8个月的随访中未观察到复发。分离物的分子鉴定基于PCR扩增和β-微管蛋白基因的测序。确定了黄曲霉

结论

我们的案例突出了骨髓炎患者和软组织受累的微生物学研究的相关性。发现FDG-PET / CT扫描是揭示疾病范围和评估对抗真菌治疗反应的有用工具。

更新日期:2019-05-22
down
wechat
bug