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Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)
Intensive Care Medicine Experimental Pub Date : 2019-07-01 , DOI: 10.1186/s40635-019-0230-9
Nicole P Juffermans 1 , Marcus Schultz 1 , Lieuwe D Bos 1 , Oscar Penuelas 2, 3 , John Laffey 4 , Jose A Lorente 2, 3
Affiliation  

Current treatment of acute respiratory distress syndrome (ARDS) in critically ill patients is limited to supportive measures including mechanical ventilation. It is our view that effective therapies for ARDS can only be found through experimental and translational science that seeks to better understand the mechanisms of injury and identify therapeutic approaches, using pre-clinical models of acute lung injury that closely mimic the clinical syndrome of ARDS. This editorial gives examples of ways in which translational science contributes to the development of more specific measures against ARDS in the critically ill. In order to improve focus on this essential research as well as to enhance collaborative research efforts, a Translational Biology Group was founded within the European Society of Intensive Care Medicine. INSPIRES is an international symposium on translational research in lung injury as well as in other areas of critical illness, intended to serve as a platform for the translational biology working group. This issue of ICMx is dedicated to the proceedings of INSPIRES III.

中文翻译:

为什么转化研究很重要:第三届急性肺损伤转化研究国际研讨会论文集(INSPIRES III)

目前对危重患者的急性呼吸窘迫综合征 (ARDS) 的治疗仅限于支持性措施,包括机械通气。我们认为,只有通过实验和转化科学才能找到有效的 ARDS 疗法,这些科学旨在更好地了解损伤机制并确定治疗方法,使用与 ARDS 临床综合征非常相似的急性肺损伤临床前模型。这篇社论举例说明了转化科学有助于制定针对重症患者的 ARDS 的更具体措施的方式。为了提高对这项重要研究的关注并加强合作研究工作,在欧洲重症监护医学学会内成立了一个转化生物学小组。INSPIRES 是一个关于肺损伤以及其他危重疾病领域转化研究的国际研讨会,旨在作为转化生物学工作组的平台。本期 ICMx 专门介绍 INSPIRES III 的程序。
更新日期:2019-07-01
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