The use of musculoskeletal allografts has become increasingly popular among surgeons. The purpose of this review is to highlight the procurment and delievery process of fresh osteochondral allografts in the United States. The four distributors of fresh osteochondral allografts in the United States were contacted. Surveys containing quantitative and qualitative sections concerning the procurement and processing of osteochondral allograft tissue were obtained. Our results showed an average of 13 ± 4.24 years of experience with osteochondral allografts. The average donor age ranged from 13.5 ± 3 to 37.5 ± 5 years, with an average age of 27 ± 2.83 years. All donors were between ages 12 and 45 years old. The percentage of screened donors that were accepted for allograft transplant was consistent at 70–75% for 3 out of the 4 tissue banks. The percentage of grafts that expire without implantation ranged from 20% to 29%. Maximum shipping time varied between 24 and 96 hours. Each tissue bank used its own proprietary storage medium. The time from donor death to the harvest of allograft tissue was < 24 hours. The most commonly requested osteochondral allograft tissue for all banks was the medial femoral condyle. The market share of fresh allografts is as follows: Joint Restoration Foundation (JRF) 59.9%, Muskuloskeletal Transplant Foundation (MTF) 15.3%, LifeNet Health (LN) 14.5%, and Regeneration Technology Incorporated (RTI) 10.2%, with approximately 4700 fresh allografts distributed in 2018. This compiled data from the four tissue banks that supply fresh osteochondral allograft in the United States provides important background information for patients and orthopaedic surgeons.

中文翻译：

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美国的新鲜骨软骨移植：组织库处理的当前状态。

肌肉骨骼同种异体移植物的使用在外科医生中越来越流行。这篇综述的目的是强调在美国新鲜骨软骨移植的采购和解除过程。已联系了美国同种异体骨软骨移植的四个分销商。获得了包含有关骨软骨同种异体组织的采购和加工的定量和定性部分的调查。我们的研究结果显示，平均平均有13±4.24年的骨软骨移植经验。供体的平均年龄为13.5±3至37.5±5岁，平均年龄为27±2.83岁。所有捐助者的年龄都在12至45岁之间。4个组织库中有3个的接受同种异体移植的筛选供体百分比一致为70-75％。未经植入而过期的移植物百分比范围为20％至29％。最长运输时间在24到96小时之间。每个组织库都使用其自己的专有存储介质。从供体死亡到同种异体组织收获的时间少于24小时。所有银行最常要求的骨软骨同种异体移植组织是股内侧media。新鲜同种异体移植的市场份额如下：联合修复基金会（JRF）59.9％，肌肉骨骼移植基金会（MTF）15.3％，LifeNet Health（LN）14.5％和再生技术有限公司（RTI）10.2％，其中约有4700种新鲜同种异体移植于2018年分发。该汇总的数据来自提供美国新鲜骨软骨移植的四个组织库，为患者和整形外科医生提供了重要的背景信息。