Low serum 25-hydroxyvitamin D [25(OH)D] concentrations are associated with a high risk of insulin resistance and Type 2 diabetes mellitus in adults. However, it is unknown whether this is the case for American collegiate football and rugby football athletes. This study investigated the associations between serum 25(OH)D concentrations and glucose profiles in male collegiate football athletes. Thirty-four collegiate athletes (13 American football players and 21 rugby football players) aged 21 years were recruited. Their body fat percent and visceral fat area were measured by dual-energy X-ray absorptiometry and magnetic resonance imaging, respectively. The participants completed an oral glucose tolerance test (75 g glucose) with venous blood samples obtained at time points 0, 30, 60, 90, and 120 min for the determination of plasma glucose and serum insulin concentrations. Fasting serum 25(OH)D concentrations were also measured. The prevalence of vitamin D deficiency and insufficiency was 17.6% and 58.8%, respectively. The serum 25(OH)D concentrations were negatively associated with the increments in the areas under the curve (iAUC) for glucose (r = -.429, p = .011) and were borderline significantly correlated with the Matsuda index (r = -.303, p = .082). No relationships were observed between the serum 25(OH)D concentrations and other glucose profiles. Multiple stepwise regression analysis of glucose iAUC concentrations as the dependent variable indicated that the serum 25(OH)D concentrations, but not body fat indicators, were independently associated with glucose iAUC (β = -0.390, p = .025). The serum 25(OH)D concentrations were only an independent predictor for glucose iAUC in male collegiate football athletes, suggesting that increased 25(OH)D concentrations would be helpful for maintaining glucose homeostasis.

中文翻译：

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男大学生足球运动员血清25-羟维生素D浓度与葡萄糖分布的关联。

低血清25-羟基维生素D [25（OH）D]浓度与成人胰岛素抵抗和2型糖尿病的高风险有关。但是，对于美国大学橄榄球和橄榄球运动员是否如此，情况尚不得而知。这项研究调查了男性大学橄榄球运动员的血清25（OH）D浓度与血糖分布之间的关联。招募了21名21岁的大学运动员（13名美国橄榄球运动员和21名橄榄球运动员）。他们的体脂百分比和内脏脂肪面积分别通过双能X射线吸收法和磁共振成像测量。参与者完成了口服葡萄糖耐量试验（75 g葡萄糖），并在0、30、60、90，120分钟用于测定血浆葡萄糖和血清胰岛素浓度。还测定了空腹血清25（OH）D的浓度。维生素D缺乏和不足的患病率分别为17.6％和58.8％。血清25（OH）D浓度与葡萄糖曲线下面积（iAUC）的增加呈负相关（r = -.429，p = .011），并且与松田指数显着相关（r =- .303，p = .082）。血清25（OH）D浓度与其他葡萄糖曲线之间没有相关性。葡萄糖iAUC浓度作为因变量的多步逐步回归分析表明，血清25（OH）D浓度（而非体脂指标）与葡萄糖iAUC独立相关（β= -0.390，p = .025）。