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Percutaneous reinforced osteoplasty for long bone metastases: a feasibility study.
Skeletal Radiology ( IF 2.1 ) Pub Date : 2019-08-04 , DOI: 10.1007/s00256-019-03288-9
Nischal Koirala 1, 2 , Gordon McLennan 2, 3
Affiliation  

OBJECTIVE While percutaneous osteoplasty is common for the treatment of vertebral fractures, low strength of fixation remains a major challenge for use in metastatic weight-bearing bones. With stent, wire, and cement augmentation, this study explores the feasibility of percutaneous reinforced osteoplasty for use in correcting long bone fractures. MATERIALS AND METHODS Fifteen explanted swine femora were randomly assigned into three groups. Group 1 (n = 5) was native (intact) bones without any intervention (control), group 2 (n = 5) received cementoplasty, and group 3 (n = 5) received stent and wire scaffolding ("rebar") in addition to cementoplasty. All treatment procedures were performed under fluoroscopic guidance. Mechanical strength of fracture fixation was quantified by peak load to failure, stiffness, work done to fracture, and fatigue testing with four-point bend test. RESULTS Percutaneous osteoplasty with or without reinforcement was successfully achieved in all specimens. The respective peak load at failure, flexural stiffness, and work done to fracture (mean ± SEM) for group 1 was 2245 ± 168 N, 14.77 ± 1.3 Nm/degree, and 4854 ± 541 Nmm; group 2 was 468 ± 81 N, 3.9 ± 0.5 Nm/degree, and 401 ± 56 Nmm; and group 3 was 594 ± 90 N, 4.42 ± 0.4 Nm/degree, and 522 ± 54 Nmm. The mean cyclic displacement for groups 1, 2, and 3 were 0.15, 0.58, and 0.48 mm, respectively, at 220-240 N loading. CONCLUSIONS While percutaneous reinforced osteoplasty with stent, wire, and cement augmentation resulted in improved mechanical strength in restored bones, it did not differ significantly from specimens that underwent exclusive cementoplasty. With the improvement of fracture strength, the concept may be applicable for prevention or treatment of pathological fractures.

中文翻译:

经皮加强骨成形术治疗长骨转移:可行性研究。

目的虽然经皮整形术通常用于治疗椎骨骨折,但固定强度低仍是转移性承重骨骼使用的主要挑战。通过支架,金属丝和骨水泥的增强,本研究探讨了经皮增强骨成形术用于矫正长骨骨折的可行性。材料与方法将十五只外植猪股骨随机分为三组。第1组(n = 5)是未经任何干预(对照)的天然(完整)骨骼,第2组(n = 5)接受了骨水泥成形术,第3组(n = 5)还接受了支架和金属丝支架(“钢筋”)进行骨水泥成形术。所有治疗程序均在荧光镜检查下进行。骨折固定的机械强度通过破坏的峰值载荷,刚度,断裂功,疲劳测试和四点弯曲测试。结果在所有标本中均成功完成了经皮或不经加固的骨成形术。第一组的破坏,弯曲刚度和断裂功的峰值载荷分别为2245±168 N,14.77±1.3 Nm /度和4854±541 Nmm。第2组为468±81 Nmm,3.9±0.5 Nm /度和401±56 Nmm; 第3组为594±90 Nmm,4.42±0.4 Nm /度和522±54 Nmm。第1、2和3组在220-240 N负荷下的平均循环位移分别为0.15、0.58和0.48 mm。结论虽然采用支架,金属丝和骨水泥增强的经皮增强骨成形术可改善恢复的骨骼的机械强度,但与仅进行骨水泥成形术的标本没有显着差异。随着断裂强度的提高,
更新日期:2020-01-21
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