In the era of personalized medicine, the management of oncological patients requires a translational and multidisciplinary approach. During early phases of cancer development, biochemical alterations of cell metabolism occur much before the formation of detectable tumour masses. Current molecular imaging techniques, targeted to the study of molecular kinetics, employ molecular tracers capable of detecting cancer lesions with both high sensitivity and specificity while also providing essential information for both prognosis and therapy. On the contrary, complementary and crucial information is provided by histopathological examination and ancillary techniques such as immunohistochemistry. Thus, the successful collaboration between diagnostic imaging and anatomic pathology can represent a fundamental step in the "tortuous" but decisive path towards personalized medicine.

中文翻译：

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结合诊断成像和病理学以改善癌症的诊断和预后。

在个性化医疗时代，肿瘤患者的管理需要采用转化和多学科的方法。在癌症发展的早期阶段，细胞代谢的生化改变早在可检测到的肿瘤块形成之前就发生了。当前的分子成像技术针对分子动力学研究，采用分子示踪剂，能够以高灵敏度和特异性检测癌症病变，同时还为预后和治疗提供重要信息。相反，组织病理学检查和免疫组织化学等辅助技术提供了补充和重要的信息。因此，诊断成像和解剖病理学之间的成功合作可以代表迈向个性化医疗的“曲折”但决定性的道路上的基本一步。