We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 117 Mexicans from the state of San Luis Potosí living in the city of San Luis Potosí (N = 30) and rural communities (N = 87), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state include 13 Native American, six European, two African and two Asian haplotypes. Admixture estimates revealed that the main genetic components are Native American (52.72 ± 0.66% by ML; 48.29% of Native American haplotypes) and European (34.62 ± 4.28% by ML; 32.48% of European haplotypes), and a relatively high African genetic component (12.66 ± 4.61% by ML; 10.26% of African haplotypes).

我们通过基于PCR-SSP的生活在San LuisPotosí州的117名墨西哥人的打字研究，研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因。 N = 30）和农村社区（N = 87），以获取有关等位基因和单倍型频率的信息。我们发现，该州最常见的单元型包括13个美洲原住民，六个欧洲，两个非洲和两个亚洲单元型。外加剂估计显示，主要的遗传成分是美洲原住民（按ML分类为52.72±0.66％；美国原住民单倍型为48.29％）和欧洲（按ML分类为34.62±4.28％；欧洲单倍型为32.48％），以及非洲遗传成分相对较高（按ML计为12.66±4.61％；非洲单倍型为10.26％）。