We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1113 Mexicans from the state of Veracruz living in the cities of Coatzacoalcos (N = 55), Orizaba (N = 60), Córdoba (N = 56), Poza Rica (N = 45), Veracruz (N = 171), Xalapa (N = 187) and rural communities (N = 539) to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes include 12 Native American haplotypes. Admixture estimates revealed that the main genetic components are Native American (64.93 ± 1.27% by ML; 55.10% of Native American haplotypes) and European (26.56 ± 0.89% by ML; 28.38% of European haplotypes), and a relatively high African genetic component (8.52 ± 1.82% by ML; 8.78% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）基于PCR-SSP的等位基因，来自居住在Coatzacoalcos（N = 55），Orizaba（N = 60），Córdoba（N = 56），Poza Rica（N = 45）等城市的韦拉克鲁斯州的1113名墨西哥人，韦拉克鲁斯（N = 171），哈拉帕（N = 187）和农村社区（N = 539）获得有关等位基因和单倍型频率的信息。我们发现，最常见的单倍型包括12个美国原住民单倍型。外加剂估计显示，主要的遗传成分是美洲原住民（按ML分类为64.93±1.27％；美国原住民单倍型为55.10％）和欧洲（按ML分类为26.56±0.89％；欧洲单倍型为28.38％），以及相对较高的非洲遗传成分（按ML值分别为8.52±1.82％；非洲单倍型的8.78％）。