Finding DNA sites with high potential for the formation of hairpin/cruciform structures is an important task. Previous works studied the distances between adjacent reversed complement words (symmetric word pairs) and also for non-adjacent words. It was observed that for some words a few distances were favoured (peaks) and that in some distributions there was strong peak regularity. The present work extends previous studies, by improving the detection and characterization of peak regularities in the symmetric word pairs distance distributions of the human genome. This work also analyzes the location of the sequences that originate the observed strong peak periodicity in the distance distribution. The results obtained in this work may indicate genomic sites with potential for the formation of hairpin/cruciform structures.

中文翻译：

---

人类基因组中对称词之间的距离分布：规则峰分析。

寻找具有高潜力形成发夹/十字形结构的DNA位点是一项重要任务。先前的作品研究了相邻的反向补词（对称词对）之间以及非相邻词之间的距离。可以观察到，对于某些词而言，优选距离（峰值）有几个，并且在某些分布中有很强的峰值规律性。本工作通过改善人类基因组对称词对距离分布中峰值规律的检测和表征，扩展了以前的研究。这项工作还分析了在距离分布中产生观察到的强峰值周期性的序列的位置。在这项工作中获得的结果可能表明有可能形成发夹/十字形结构的基因组位点。