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Clinical Usefulness of Self-Rated Olfactory Performance-A Data Science-Based Assessment of 6000 Patients.
Chemical Senses ( IF 3.5 ) Pub Date : 2019-05-12 , DOI: 10.1093/chemse/bjz029
Jörn Lötsch 1, 2 , Thomas Hummel 3
Affiliation  

In clinical practice, with its time constraints, a frequent conclusion is that asking about the ability to smell may suffice to detect olfactory problems. To address this question systematically, 6049 subjects were asked about how well they can perceive odors, with 5 possible responses. Participants presented at a University Department of Otorhinolaryngology, where olfactory testing was part of the routine investigation performed in patients receiving surgery at the clinic (for various reasons). According to an odor identification test, 1227 subjects had functional anosmia and 3113 were labeled with normosmia. Measures of laboratory test performance were used to assess the success of self-estimates to capture the olfactory diagnosis. Ratings of the olfactory function as absent or impaired provided the diagnosis of anosmia at a balanced accuracy of 79%, whereas ratings of good or excellent indicated normosmia at a balanced accuracy of 64.6%. The number of incorrect judgments of anosmia increased with age, whereas false negative self-estimates of normosmia became rarer with increasing age. The subject's sex was irrelevant in this context. Thus, when asking the question "How well can you smell odors?" and querying standardized responses, fairly accurate information can be obtained about whether or not the subject can smell. However, this has to be completed with the almost 30% (355 subjects) of anosmic patients who judged their ability to smell as at least "average." Thus, olfactory testing using reliable and validated tests appears indispensable.

中文翻译:

自测嗅觉性能的临床实用性-基于数据科学的6000名患者的评估。

在时间限制下的临床实践中,一个经常得出的结论是,询问气味的能力可能足以检测出嗅觉问题。为了系统地解决这个问题,向6049名受试者询问了他们对气味的感知程度,并做出了5种可能的回答。参加者在大学耳鼻咽喉科进行了介绍,其中嗅觉测试是在诊所接受手术的患者进行的例行调查的一部分(出于各种原因)。根据气味识别测试,有1227名受试者患有功能性失眠症,而3113名受试者被标记为正常性失眠症。实验室测试表现的量度用于评估自我估计是否成功以捕获嗅觉诊断。嗅觉功能缺失或受损的评分以79%的平衡准确度提供了对失眠的诊断,而良好或优良的正常睡眠评分以64.6%的平衡准确度进行了诊断。对失眠症的错误判断随着年龄的增长而增加,而对失眠症的假阴性自我估计随着年龄的增长而变得越来越少。在这种情况下,受试者的性别无关紧要。因此,在问“您闻起来有多臭吗?”的问题时 通过查询标准化响应,可以获得关于受试者是否会闻到的相当准确的信息。然而,这必须由近30%(355名受试者)的厌氧症患者完成,他们认为他们的嗅觉能力至少为“平均水平”。因此,使用可靠且经过验证的测试进行嗅觉测试似乎是必不可少的。而正常或正常的评分则表明其正常睡眠状态的准确性为64.6%。对失眠症的错误判断随着年龄的增长而增加,而对失眠症的假阴性自我估计随着年龄的增长而变得越来越少。在这种情况下,受试者的性别无关紧要。因此,在问“您闻起来有多臭吗?”的问题时 通过查询标准化响应,可以获得关于受试者是否会闻到的相当准确的信息。然而,这必须由近30%(355名受试者)的厌氧症患者完成,他们认为他们的嗅觉能力至少为“平均水平”。因此,使用可靠且经过验证的测试进行嗅觉测试似乎是必不可少的。而正常或正常的评分则表明其正常睡眠状态的准确性为64.6%。对失眠症的错误判断随着年龄的增长而增加,而对失眠症的假阴性自我估计随着年龄的增长而变得越来越少。在这种情况下,受试者的性别无关紧要。因此,在问“您闻起来有多臭吗?”的问题时 通过查询标准化响应,可以获得关于受试者是否会闻到的相当准确的信息。然而,这必须由近30%(355名受试者)的厌氧症患者完成,他们认为他们的嗅觉能力至少为“平均水平”。因此,使用可靠且经过验证的测试进行嗅觉测试似乎是必不可少的。对失眠症的错误判断随着年龄的增长而增加,而对失眠症的假阴性自我估计随着年龄的增长而变得越来越少。在这种情况下,受试者的性别无关紧要。因此,在问“您闻起来有多臭吗?”的问题时 通过查询标准化响应,可以获得关于受试者是否会闻到的相当准确的信息。然而,这必须由近30%(355名受试者)的厌氧症患者完成,他们认为他们的嗅觉能力至少为“平均水平”。因此,使用可靠且经过验证的测试进行嗅觉测试似乎是必不可少的。对失眠症的错误判断随着年龄的增长而增加,而对失眠症的假阴性自我估计随着年龄的增长而变得越来越少。在这种情况下,受试者的性别无关紧要。因此,在问“您闻起来有多臭吗?”的问题时 通过查询标准化响应,可以获得关于受试者是否会闻到的相当准确的信息。然而,这必须由近30%(355名受试者)的厌氧症患者完成,他们认为他们的嗅觉能力至少为“平均水平”。因此,使用可靠且经过验证的测试进行嗅觉测试似乎是必不可少的。
更新日期:2019-11-01
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