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Lymphocytic subsets play distinct roles in heart diseases.
Theranostics ( IF 12.4 ) Pub Date : 2019-01-01 , DOI: 10.7150/thno.33112
Jing Wang 1 , Yi Duan 1 , Joost Pg Sluijter 2, 3 , Junjie Xiao 1
Affiliation  

Heart diseases are one of the leading causes of death for humans in the world. Increasing evidence has shown that myocardial injury induced innate and adaptive immune responses upon early cellular damage but also during chronic phases post-injury. The immune cells can not only aggravate the injury but also play an essential role in the induction of wound healing responses, which means they play a complex role throughout the acute inflammatory response and reparative response after cardiac injury. This review will summarize the current experimental and clinical evidence of lymphocytes, one of the major types of immune cells, participate in heart diseases and try to explain the possible role of these immune cells following cardiac injury.

中文翻译:

淋巴细胞亚群在心脏病中起着不同的作用。

心脏病是世界上导致人类死亡的主要原因之一。越来越多的证据表明,心肌损伤会在早期细胞损伤后以及损伤后的慢性期诱导先天性和适应性免疫反应。免疫细胞不仅可以加重损伤,而且在诱导伤口愈合反应中起重要作用,这意味着它们在心脏损伤后的整个急性炎症反应和修复反应中起着复杂的作用。这篇综述将总结淋巴细胞的主要实验和临床证据,淋巴细胞是免疫细胞的主要类型之一,参与心脏病,并试图解释这些免疫细胞在心脏损伤后的可能作用。
更新日期:2019-01-01
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