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Disease-Modifying Effect of Adiponectin in Model of α-Synucleinopathies.
Annals of Clinical and Translational Neurology ( IF 5.3 ) Pub Date : 2014-07-03 , DOI: 10.1002/acn3.77
Kazunari Sekiyama 1 , Masaaki Waragai 1 , Hiroyasu Akatsu 2 , Shuei Sugama 3 , Takato Takenouchi 4 , Yoshiki Takamatsu 1 , Masayo Fujita 1 , Akio Sekigawa 1 , Edward Rockenstein 5 , Satoshi Inoue 6 , Albert R La Spada 7 , Eliezer Masliah 5 , Makoto Hashimoto 1
Affiliation  

Growing evidence suggests that neurodegenerative diseases are associated with metabolic disorders, but the mechanisms are still unclear. Better comprehension of this issue might provide a new strategy for treatment of neurodegenerative diseases. We investigated possible roles of adiponectin (APN), the antidiabetes protein, in the pathogenesis of α‐synucleinopathies.

中文翻译:

脂联素在α-突触核蛋白病模型中的疾病修饰作用。

越来越多的证据表明,神经退行性疾病与代谢紊乱有关,但其机制尚不清楚。更好地理解这个问题可能为治疗神经退行性疾病提供新的策略。我们研究了脂联素 (APN)(抗糖尿病蛋白)在α-突触核蛋白病发病机制中的可能作用。
更新日期:2014-07-03
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