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Aerobic training reduces blood pressure and waist circumference and increases HDL-c in metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
Journal of the American Society of Hypertension Pub Date : 2018-06-28 , DOI: 10.1016/j.jash.2018.06.007
Ítalo Ribeiro Lemes 1 , Bruna Camilo Turi-Lynch 2 , Iván Cavero-Redondo 3 , Stephanie Nogueira Linares 4 , Henrique Luiz Monteiro 5
Affiliation  

The objective of this study is to estimate the effect of aerobic training (AT) on metabolic syndrome (MetS) outcomes. The Medline, EMBASE, SPORTDiscus, The Cochrane Library, and PEDro databases were searched from inception to May 2017. Two independent reviewers selected the studies and assessed their quality and data. The pooled mean differences between intervention groups and the control group were calculated using a random-effect model. Only randomized controlled trials that compared the effect of AT on MetS with a control group were included. Seventeen published studies were included in the meta-analysis. Systolic and diastolic blood pressure were significantly reduced (-5.11 mmHg [95% confidence interval [CI] -7.36, -2.85] and -2.97 mmHg [-4.99, -0.94], respectively), following AT. There was also a significant reduction in waist circumference (-2.18 cm [95% CI -3.75, -0.62]) and a significant increase in high-density lipoprotein cholesterol (95% CI -3.15 mg/dL [-5.30, -1.01]). The pooled effect showed a reduction of -7.64 mg/dL [95% CI -17.65, 2.37] in triglycerides and -1.36 mg/dL [95% CI -4.11, 1.40] in fasting glucose. This systematic review and meta-analysis provides an overview of the evidence supporting AT as an effective approach to reduce blood pressure levels and waist circumference and increase high-density lipoprotein cholesterol levels. These changes may help to reduce the risk of stroke mortality and mortality from heart disease in people with MetS.

中文翻译:

有氧训练可降低代谢综合征中的血压和腰围,并增加HDL-c:随机对照试验的系统评价和荟萃分析。

这项研究的目的是评估有氧训练(AT)对代谢综合征(MetS)结局的影响。从开始到2017年5月,对Medline,EMBASE,SPORTDiscus,Cochrane图书馆和PEDro数据库进行了搜索。两名独立的评审员选择了研究并评估了其质量和数据。使用随机效应模型计算干预组与对照组之间的合并平均差异。仅包括将AT对MetS的作用与对照组进行比较的随机对照试验。荟萃分析包括十七项已发表的研究。在AT后,收缩压和舒张压明显降低(分别为-5.11 mmHg [95%置信区间[CI] -7.36,-2.85]和-2.97 mmHg [-4.99,-0.94])。腰围也明显减少(-2.18 cm [95%CI -3.75,-0.62]),高密度脂蛋白胆固醇显着增加(95%CI -3.15 mg / dL [-5.30,-1.01] )。合并的结果显示,甘油三酸酯减少-7.64 mg / dL [95%CI -17.65,2.37],空腹葡萄糖减少-1.36 mg / dL [95%CI -4.11,1.40]。这项系统的综述和荟萃分析提供了支持AT作为降低血压和腰围并增加高密度脂蛋白胆固醇水平的有效方法的证据的概述。这些变化可能有助于降低MetS患者中风死亡率和心脏病死亡率的风险。合并的结果显示,甘油三酸酯减少-7.64 mg / dL [95%CI -17.65,2.37],空腹葡萄糖减少-1.36 mg / dL [95%CI -4.11,1.40]。这项系统的综述和荟萃分析提供了支持AT作为降低血压和腰围并增加高密度脂蛋白胆固醇水平的有效方法的证据的概述。这些变化可能有助于降低MetS患者中风死亡率和心脏病死亡率的风险。合并的结果显示,甘油三酸酯减少-7.64 mg / dL [95%CI -17.65,2.37],空腹葡萄糖减少-1.36 mg / dL [95%CI -4.11,1.40]。这项系统的综述和荟萃分析提供了支持AT作为降低血压和腰围并增加高密度脂蛋白胆固醇水平的有效方法的证据的概述。这些变化可能有助于降低MetS患者中风死亡率和心脏病死亡率的风险。
更新日期:2019-11-01
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