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The Current State of Pediatric Acute Respiratory Distress Syndrome.
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2019-06-27 , DOI: 10.1089/ped.2019.0999
Kirsten E Orloff 1 , David A Turner 1 , Kyle J Rehder 1
Affiliation  

Pediatric acute respiratory distress syndrome (PARDS) is a significant cause of morbidity and mortality in children. Children with PARDS often require intensive care admission and mechanical ventilation. Unfortunately, beyond lung protective ventilation, there are limited data to support our management strategies in PARDS. The Pediatric Acute Lung Injury Consensus Conference (PALICC) offered a new definition of PARDS in 2015 that has improved our understanding of the true epidemiology and heterogeneity of the disease as well as risk stratification. Further studies will be crucial to determine optimal management for varying disease severity. This review will present the physiologic basis of PARDS, describe the unique pediatric definition and risk stratification, and summarize the current evidence for current standards of care as well as adjunctive therapies.

中文翻译:

小儿急性呼吸窘迫综合征的现状。

小儿急性呼吸窘迫综合征(PARDS)是儿童发病和死亡的重要原因。PARDS儿童通常需要重症监护和机械通气。不幸的是,除了肺部保护性通气之外,在PARDS中,仅有有限的数据支持我们的管理策略。小儿急性肺损伤共识会议(PALICC)在2015年提出了PARDS的新定义,这加深了我们对疾病的真正流行病学和异质性以及风险分层的了解。进一步的研究对于确定针对不同疾病严重程度的最佳治疗方法至关重要。这篇评论将介绍PARDS的生理基础,描述独特的儿科定义和风险分层,
更新日期:2019-11-01
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