The supplementation of livestock rations with herbs containing bioactive components, such as rosmarinic acid (RA), have shown promising results as a natural feed additive in promoting growth, productive and reproductive performance, feed utilization, fertility, anti-oxidant status and immunologic indices. Furthermore, RA reportedly reduces the risks of various animal diseases and mitigates side effects of chemical and synthetic drugs. RA is a natural polyphenol present in several Lamiaceae herbs like Perilla frutescens, and RA is becoming an integral component of animal nutrition as it counters the effect of reactive oxygen species induced in the body as a consequence of different kinds of stressors. Studies have further ascertained the capability of RA to work as an anti-microbial, immunomodulatory, anti-diabetic, anti-allergic, anti-inflammatory, hepato- and renal-protectant agent, as well as to have beneficial effects during skin afflictions. Additionally, RA is favored in meat industries due to enhancing the quality of meat products by reportedly improving shelf-life and imparting desirable flavor. This review describes the beneficial applications and recent findings with RA, including its natural sources, modes of action and various useful applications in safeguarding livestock health as well as important aspects of human health.

中文翻译：

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迷迭香酸：作用方式、药用价值和健康益处

用含有迷迭香酸 (RA) 等生物活性成分的草药补充牲畜口粮，作为一种天然饲料添加剂，在促进生长、生产和繁殖性能、饲料利用率、生育力、抗氧化状态和免疫指标方面显示出可喜的结果。此外，据报道，RA 可降低各种动物疾病的风险并减轻化学和合成药物的副作用。RA 是一种天然多酚，存在于几种唇形科植物中，如紫苏，并且 RA 正在成为动物营养的一个组成部分，因为它可以对抗由于不同种类的压力源而在体内诱导的活性氧的影响。研究进一步确定了 RA 作为抗微生物、免疫调节、抗糖尿病、抗过敏、抗炎、肝和肾保护剂的能力，以及在皮肤病期间具有有益作用。此外，RA 在肉类工业中受到青睐，因为据报道通过提高保质期和赋予理想的风味来提高肉类产品的质量。这篇综述描述了 RA 的有益应用和最近的发现，包括其天然来源、作用方式和在保护牲畜健康以及人类健康的重要方面的各种有用应用。