We investigated the effects of the antiparasitic drug ivermectin on the dung beetles Copris acutidens Motschulsky, Onthophagus bivertex Heyden, O. lenzii Harold and Phelotrupes auratus auratus Motschulsky in Japan. Ivermectin was detected in cattle dung from 1 to 3 or 7 days post-treatment, with a peak at 3 days post-treatment in two pour-on administrations (500 µg kg−1). In C. acutidens, adult survivals and numbers of brood balls were significantly reduced in dung collected at 3 and 7 days post-treatment, and adult emergence rates were significantly decreased in dung collected at 7 and 14 days post-treatment. Feeding activity of C. acutidens was inhibited in dung collected at 3 days post-treatment, but was not significantly different from that seen in control dung at 7 and 14 days post-treatment. In O. bivertex and O. lenzii, there were no effects of ivermectin on adult survival or feeding activities, but the numbers of brood balls of O. bivertex constructed in dung collected at 3 and 7 days post-treatment were significantly lower than observed with control dung. The adult emergence rates of O. bivertex and O. lenzii were significantly reduced in dung collected at 1 to 3 and 1 to 7 days post-treatment, respectively. In P. auratus, there were no effects of ivermectin on adult survival, oviposition, feeding activity, or larval survival (until the third instar) in dung at 3 days post-treatment. The environmental risks affecting the populations of dung beetles in Japan are discussed.

中文翻译：

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伊维菌素对日本四种蜣螂（鞘翅目：金龟子科和地壳虫科）生存、繁殖和摄食活动的毒理学影响

我们研究了抗寄生虫药物伊维菌素对粪甲虫的影响苦瓜莫舒尔斯基，食蚁兽海登，O. lenzii哈罗德和金针菇日本的莫舒尔斯基。处理后 1 至 3 或 7 天在牛粪中检测到伊维菌素，在两次浇注给药（500 µg kg-1）中在处理后 3 天达到峰值-1）。在C. acutidens处理后 3 天和 7 天收集的粪便中成虫存活率和育雏球数量显着减少，处理后 7 天和 14 天收集的粪便中成虫出苗率显着降低。的喂养活动C. acutidens在处理后 3 天收集的粪便中 20 被抑制，但与处理后 7 天和 14 天在对照粪便中观察到的没有显着差异。在O. bivertex和O. lenzii，伊维菌素对成虫生存或摄食活动没有影响，但育雏球的数量O. bivertex在处理后 3 天和 7 天收集的粪便中构建的粪便显着低于用对照粪便观察到的。成虫出现率O. bivertex和O. lenzii分别在处理后 1 至 3 天和 1 至 7 天收集的粪便中显着减少。在P. auratus，在处理后 3 天，伊维菌素对粪便中的成虫存活、产卵、摄食活动或幼虫存活（直到第三龄）没有影响。讨论了影响日本蜣螂种群的环境风险。