The impact of the hobo transposable element in the global reorganization of the Drosophila melanogaster genome has been investigated in transgenic lines generated by the injection of hobo elements into the Hikone strain, which lacked them previously. Extensive surveys of transgenic lines followed for 250 generations have identified 13 inversions with hobo inserts at most breakpoints. One of these inversions is pericentric on chromosome 2. It has been maintained in the line where it was discovered and in several sublines at frequencies from 0.19 to 0.45, generating stable chromosomal polymorphisms, similar to cosmopolitan paracentric inversions in natural populations. Individuals homozygous for this inversion were viable and fertile, allowing the creation of a new homozygous strain. Hobo elements were still active after 250 generations.

中文翻译：

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由黑腹果蝇转基因品系中的流浪汉转座元件产生的大的中心倒位的维持

hobo 转座因子在黑腹果蝇基因组全局重组中的影响已在通过将 hobo 元素注入 Hikone 菌株而产生的转基因品系中进行了研究，该菌株以前缺乏它们。对转基因品系进行了 250 代的广泛调查，已经确定了 13 个在大多数断点处带有流浪汉插入物的倒位。这些倒位之一是在 2 号染色体上的周着丝点。它一直保持在它被发现的系和几个亚系中，频率从 0.19 到 0.45，产生稳定的染色体多态性，类似于自然种群中的世界性偏中心倒位。这种倒位的纯合个体是有活力和可育的，允许产生新的纯合菌株。Hobo元素在250代之后仍然活跃。