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High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study.
Cardiovascular Engineering and Technology ( IF 1.8 ) Pub Date : 2019-04-01 , DOI: 10.1007/s13239-019-00410-9 Viviana Mancini 1 , Aslak W Bergersen 2 , Jan Vierendeels 3 , Patrick Segers 1 , Kristian Valen-Sendstad 2
中文翻译:
狭窄后患者特定颈动脉狭窄流体动力学中的高频波动:计算流体动力学策略研究。
更新日期:2019-04-01
Cardiovascular Engineering and Technology ( IF 1.8 ) Pub Date : 2019-04-01 , DOI: 10.1007/s13239-019-00410-9 Viviana Mancini 1 , Aslak W Bergersen 2 , Jan Vierendeels 3 , Patrick Segers 1 , Kristian Valen-Sendstad 2
Affiliation
Purpose
Screening of asymptomatic carotid stenoses is performed by auscultation of the carotid bruit, but the sensitivity is poor. Instead, it has been suggested to detect carotid bruit as neck’s skin vibrations. We here take a first step towards a computational fluid dynamics proof-of-concept study, and investigate the robustness of our numerical approach for capturing high-frequent fluctuations in the post-stenotic flow. The aim was to find an ideal solution strategy from a pragmatic point of view, balancing accuracy with computational cost comparing an under-resolved direct numerical simulation (DNS) approach vs. three common large eddy simulation (LES) models (static/dynamic Smagorinsky and Sigma).Method
We found a reference solution by performing a spatial and temporal refinement study of a stenosed carotid bifurcation with constant flow rate. The reference solution \(\left( {\Delta x = 1.92 \times 10^{ - 4} \;{\text{m}},\; \Delta t = 5 \times 10^{ - 5} \;{\text{s}}} \right)\) was compared against LES for both a constant and pulsatile flow.Results
Only the Sigma and Dynamic Smagorinsky models were able to replicate the flow field of the reference solution for a pulsatile simulation, however the computational cost of the Sigma model was lower. However, none of the sub-grid scale models were able to replicate the high-frequent flow in the peak-systolic constant flow rate simulations, which had a higher mean Reynolds number.Conclusions
The Sigma model was the best combination between accuracy and cost for simulating the pulsatile post-stenotic flow field, whereas for the constant flow rate, the under-resolved DNS approach was better. These results can be used as a reference for future studies investigating high-frequent flow features.中文翻译:
狭窄后患者特定颈动脉狭窄流体动力学中的高频波动:计算流体动力学策略研究。