The incidence of type 2 diabetes mellitus (T2D) is increasing in youth, yet little is known about the underlying pathophysiology. Decreased insulin suppression of lipolysis and elevated non‐esterified free fatty acid (NEFA) concentrations are known to be associated with insulin resistance and T2D in adults, but less is known about the relationship in adolescents.

中文翻译：

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患有和不患有 2 型糖尿病的青少年的脂肪组织胰岛素抵抗。

青年人 2 型糖尿病 (T2D) 的发病率正在增加，但对其潜在的病理生理学知之甚少。已知脂肪分解的胰岛素抑制降低和非酯化游离脂肪酸 (NEFA) 浓度升高与成人的胰岛素抵抗和 T2D 相关，但对青少年的关系知之甚少。