ABSTRACT Stem cells are one of the most important sources to develope a new strategy for repairing bone lesions through tissue engineering. Osteogenic differentiation of stem cells can be affected by various factors such as biological, chemical, physiological, and physical ones. The application of ELF-EMFs has been the subject of many research in bone tissue engineering and evidence suggests that this exogenous physical stimulus can promote osteogenic differentiation in several types of cells. The purpose of this paper is to review the current knowledge on the effects of EMFs on stem cells in bone tissue engineering studies. We recapitulated and analyzed 39 articles that were focused on the application of EMFs for bone tissue engineering purposes. We tabulated scattered information from these articles for easy use and tried to provide an overview of conducted research and identify the knowledge gaps in the field.

中文翻译：

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电磁场在骨再生医学中的综合应用

摘要 干细胞是开发一种通过组织工程修复骨病变的新策略的最重要来源之一。干细胞的成骨分化受生物、化学、生理和物理等多种因素的影响。ELF-EMF 的应用一直是骨组织工程中许多研究的主题，有证据表明这种外源性物理刺激可以促进多种类型细胞的成骨分化。本文的目的是回顾有关 EMF 对骨组织工程研究中干细胞影响的当前知识。我们概括并分析了 39 篇文章，这些文章侧重于 EMF 在骨组织工程中的应用。