Glucantransferase Bgl2p is a major conserved cell wall constituent described for a wide range of yeast species. In the baker's yeast Saccharomyces cerevisiae it is the only non-covalently bound cell wall protein that cannot be released from cell walls by sequential SDS and trypsin treatment. It contains seven amyloidogenic determinants. Circular dichroism analysis and fluorescence spectroscopy with thioflavin T indicate the presence of beta-sheet structures in Bgl2p isolates. Bgl2p forms fibrils, a process that is enforced in the presence of other cell wall components. Thus the data obtained is the first evidence for amyloid-like properties of yeast cell wall protein-glucantransferase Bgl2p.

中文翻译：

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酿酒酵母细胞壁葡聚糖转移酶 Bgl2p 的淀粉样蛋白样特性：预测和实验证据。

葡聚糖转移酶 Bgl2p 是一种主要的保守细胞壁成分，适用于多种酵母物种。在面包酵母 Saccharomyces cerevisiae 中，它是唯一一种非共价结合的细胞壁蛋白，不能通过连续 SDS 和胰蛋白酶处理从细胞壁中释放出来。它包含七个淀粉样蛋白原决定簇。圆二色性分析和使用硫代黄素 T 的荧光光谱表明 Bgl2p 分离物中存在β-折叠结构。Bgl2p 形成原纤维，这是一个在其他细胞壁成分存在的情况下强制执行的过程。因此，获得的数据是酵母细胞壁蛋白-葡聚糖转移酶 Bgl2p 的淀粉样蛋白样特性的第一个证据。