In this article, some new aspects of unified cell bioenergetics are presented. From the perspective of unified cell bioenergetics certain subsequent stages of cancer development, from initiation stage, through transformation to metastasis, are analyzed. Here we show that after transformation, cancer cells are permanently exposed to reactive oxygen species, that causes continual random DNA mutations and as a result genome and chromosomal destabilizations. The modern cancer attractor hypothesis has been extended in explaining cancer development. Discussion is conducted in light of current cancerogenesis research, including bioenergetic cancer initiation, the somatic mutation theory and the tissue organization field theory. In the article reasons complicating the discovery of patterns of cancer genome changes and cancer evolution are presented. In addition certain cancer therapeutic aspects are given attention to.

中文翻译：

---

生命，疾病和死亡现象的生物能学。

本文介绍了统一细胞生物能学的一些新方面。从统一的细胞生物能学的角度，分析了癌症发展的某些后续阶段，从起始阶段到转化到转移。在这里，我们显示出转化后，癌细胞永久暴露于活性氧，导致连续的随机DNA突变，从而导致基因组和染色体失稳。现代癌症吸引子假说已经扩展到解释癌症的发展。根据当前的致癌研究进行讨论，包括生物能癌症的引发，体细胞突变理论和组织组织场理论。在本文中，提出了使癌症基因组变化和癌症进化模式的发现复杂化的原因。