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Ultrasound assessment of the polycystic ovary: international consensus definitions.
Human Reproduction Update ( IF 13.3 ) Pub Date : 2004-01-13 , DOI: 10.1093/humupd/dmg044 Adam H Balen 1 , Joop S E Laven , Seang-Lin Tan , Didier Dewailly
Human Reproduction Update ( IF 13.3 ) Pub Date : 2004-01-13 , DOI: 10.1093/humupd/dmg044 Adam H Balen 1 , Joop S E Laven , Seang-Lin Tan , Didier Dewailly
Affiliation
The polycystic ovary syndrome (PCOS) is a heterogeneous condition, the pathophysiology of which appears to be both multifactorial and polygenic. The definition of the syndrome has been much debated. Key features include menstrual cycle disturbance, hyperandrogenism and obesity. There are many extra-ovarian aspects to the pathophysiology of PCOS, yet ovarian dysfunction is central. At a recent joint ASRM/ESHRE consensus meeting, a refined definition of the PCOS was agreed, encompassing a description of the morphology of the polycystic ovary (PCO). According to the available literature, the criteria fulfilling sufficient specificity and sensitivity to define the PCO should have at least one of the following: either 12 or more follicles measuring 2-9 mm in diameter, or increased ovarian volume (> 10 cm3). If there is a follicle > 10 mm in diameter, the scan should be repeated at a time of ovarian quiescence in order to calculate volume and area. The presence of a single PCO is sufficient to provide the diagnosis. The distribution of follicles and a description of the stroma are not required in the diagnosis. Increased stromal echogenicity and/or stromal volume are specific to PCO, but it has been shown that the measurement of ovarian volume (or area) is a good surrogate for quantification of the stroma in clinical practice. A woman having PCO in the absence of an ovulation disorder or hyperandrogenism ('asymptomatic PCO') should not be considered as having PCOS, until more is known about this situation. Three-dimensional and Doppler ultrasound studies may be useful research tools but are not required in the definition of PCO. This review outlines evidence for the current ultrasound definition of the polycystic ovary and technical specifications.
中文翻译:
多囊卵巢的超声评估:国际共识定义。
多囊卵巢综合征(PCOS)是一种异质性疾病,其病理生理学似乎是多因素的和多基因的。该综合征的定义已引起广泛争议。主要特征包括月经周期紊乱,雄激素过多症和肥胖症。PCOS的病理生理学有许多卵巢外方面,但卵巢功能障碍是中心。在最近的ASRM / ESHRE联合共识会议上,同意对PCOS进行精确定义,其中包括对多囊卵巢(PCO)形态的描述。根据现有文献,满足足够的特异性和敏感性以定义PCO的标准应至少具有以下一项:直径为2-9 mm的12个或更多卵泡,或卵巢体积增加(> 10 cm3)。如果有卵泡> 直径为10毫米时,应在卵巢静止时重复扫描以计算体积和面积。单个PCO的存在足以提供诊断。诊断中不需要卵泡的分布和基质的描述。增加的基质回声性和/或基质体积是PCO所特有的,但已证明卵巢体积(或面积)的测量是临床实践中定量基质的良好替代方法。没有排卵障碍或雄激素过多症(“无症状性PCO”)的女性,不应被认为患有PCOS,除非对此情况有更多了解。三维和多普勒超声研究可能是有用的研究工具,但在PCO的定义中并不需要。
更新日期:2019-11-01
中文翻译:
多囊卵巢的超声评估:国际共识定义。
多囊卵巢综合征(PCOS)是一种异质性疾病,其病理生理学似乎是多因素的和多基因的。该综合征的定义已引起广泛争议。主要特征包括月经周期紊乱,雄激素过多症和肥胖症。PCOS的病理生理学有许多卵巢外方面,但卵巢功能障碍是中心。在最近的ASRM / ESHRE联合共识会议上,同意对PCOS进行精确定义,其中包括对多囊卵巢(PCO)形态的描述。根据现有文献,满足足够的特异性和敏感性以定义PCO的标准应至少具有以下一项:直径为2-9 mm的12个或更多卵泡,或卵巢体积增加(> 10 cm3)。如果有卵泡> 直径为10毫米时,应在卵巢静止时重复扫描以计算体积和面积。单个PCO的存在足以提供诊断。诊断中不需要卵泡的分布和基质的描述。增加的基质回声性和/或基质体积是PCO所特有的,但已证明卵巢体积(或面积)的测量是临床实践中定量基质的良好替代方法。没有排卵障碍或雄激素过多症(“无症状性PCO”)的女性,不应被认为患有PCOS,除非对此情况有更多了解。三维和多普勒超声研究可能是有用的研究工具,但在PCO的定义中并不需要。