Neonatal alloimmune neutropenia (NAIN, NAIN or NIN) is a neutrophil blood group antagonism, analogous to hemolytic disease of the fetus and newborn (HDFN) and fetal/neonatal alloimmune thrombocytopenia (FNAIT). A limited number of prospective screening studies showed that granulocyte-specific antibodies were detectable in 0.35-1.1% of random postnatal maternal samples and that the incidence of NAIN was below 0.1%. Symptoms vary from none to mild skin infections, omphalitis or more severe infections like pneumonia, sepsis, and meningitis. Treatment of neonatal infection with antibiotics and granulocyte-colony stimulating factor is advised.

中文翻译：

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新生儿同种免疫性中性粒细胞减少症

新生儿同种免疫性中性粒细胞减少症（NAIN、NAIN 或 NIN）是一种中性粒细胞血型拮抗，类似于胎儿和新生儿溶血病 (HDFN) 和胎儿/新生儿同种免疫性血小板减少症 (FNAIT)。有限数量的前瞻性筛查研究表明，在 0.35-1.1% 的随机产后母体样本中可检测到粒细胞特异性抗体，并且 NAIN 的发生率低于 0.1%。症状从无到轻度皮肤感染、脐炎或更严重的感染（如肺炎、败血症和脑膜炎）不等。建议用抗生素和粒细胞集落刺激因子治疗新生儿感染。