Cardiovascular diseases are among the leading causes of morbidity and mortality. Despite scientific and technical progress in risk prediction, diagnostics, prognostication and therapy of cardiovascular pathologies, new biomarkers and therapeutic targets remain the subject of intense research to reduce the burden of these diseases. High throughput analyses, termed "omics", are a promising avenue of research. These recently developed technical fields have revolutionized biological and medical research in a very short time. By their interdisciplinary nature, these new methods have already provided a wide vision of cell and tissue pathways and functions. Here, we review how these methods can help to discover new biomarkers and therapeutic targets in cardiovascular diseases.

中文翻译：

---

组学在心血管疾病中的转化方法。

心血管疾病是发病率和死亡率的主要原因之一。尽管在心血管疾病的风险预测、诊断、预后和治疗方面取得了科学和技术进步，但新的生物标志物和治疗靶点仍然是减轻这些疾病负担的深入研究的主题。高通量分析，称为“组学”，是一种很有前途的研究途径。这些最近开发的技术领域在很短的时间内彻底改变了生物和医学研究。由于它们的跨学科性质，这些新方法已经为细胞和组织途径和功能提供了广阔的视野。在这里，我们回顾了这些方法如何帮助发现心血管疾病的新生物标志物和治疗靶点。