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Macromolecules as targeted drugs delivery vehicles: an overview
Designed Monomers and Polymers ( IF 1.6 ) Pub Date : 2019-01-01 , DOI: 10.1080/15685551.2019.1591681
Yousaf Ali 1 , Ali Alqudah 2 , Sadiq Ahmad 3 , Shafida Abd Hamid 4 , Umar Farooq 5
Affiliation  

ABSTRACT Targeted drug delivery system improves the efficiency and safety of the therapeutic agents by managing the pharmacokinetics and pharmacodynamics of drugs. Currently, numerous drug carrier systems have been developed with different sizes, architectures and characteristics surface properties. Among different systems, macromolecules have a wide range of applications in targeted drug delivery system. The optimal drug loading potential, smooth drug releasing ability and biocompatibility are the distinguishing features that ensure the drugs delivery ability of macromolecules. This review briefly introduces some of the most commonly studied macromolecules which have been recommended as drugs delivery vehicles.

中文翻译:

作为靶向药物输送载体的大分子:概述

摘要 靶向给药系统通过管理药物的药代动力学和药效学来提高治疗药物的效率和安全性。目前,已经开发出许多具有不同尺寸、结构和特征表面性质的药物载体系统。在不同的系统中,大分子在靶向给药系统中有着广泛的应用。最佳的载药潜力、平稳的药物释放能力和生物相容性是保证大分子药物递送能力的显着特征。本综述简要介绍了一些最常研究的被推荐作为药物输送载体的大分子。
更新日期:2019-01-01
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