Insect pathogens are widely used as a tool for sustainable pest management. Their complex mode of action was thought to make them immune to the evolution of resistance; however, several examples of field-based resistance to the bacterium Bacillus thuringiensis and a granulovirus have been recorded. Here I review the scenarios where resistance has evolved and discuss the likelihood of it occurring in other entomopathogens. I highlight recent research on the factors which might influence the evolution of resistance to insect pathogens, including the role of pathogen diversity, host nutrition and transgenerational effects.

中文翻译：

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宿主对昆虫病原体抗性的演变。

昆虫病原体被广泛用作可持续虫害管理的工具。人们认为它们的复杂作用方式使它们不受抵抗力演变的影响。然而，已经记录了对苏云金芽孢杆菌和粒状病毒的基于田间抗性的几个例子。在这里，我回顾了耐药性演变的情况，并讨论了它在其他昆虫病原体中发生的可能性。我重点介绍了有关可能影响昆虫病原体抗性演变的因素的最新研究，包括病原体多样性的作用，宿主营养和转基因作用。