Cardiovascular disease in older people is often linked with cognitive impairment, particularly in domains of executive function and processing speed. Our aims examined whether carotid-femoral pulse wave velocity (PWV) related to subtle changes of executive function and processing speed. Fifty-six individuals with subjective mood and/or cognitive concerns underwent PWV and neuropsychological assessments of processing speed (Trail Making Test Part A) and executive functioning (Delis Kaplan Executive Function System Stroop Task; Trail Making Test Part B, TMT-B). Individuals with high PWV (≥12.0m/s) had poorer performance on TMT-B, compared to low PWV (<12.0m/s), and a moderate negative correlation (r = -0.38, p = .004) between PWV and TMT-B performance. Our results confirm that in older adults at-risk for cognitive decline, early markers of CVD are associated with subtle decrements in rapid set-shifting (executive function), supporting efforts towards early detection of CVD as a secondary prevention strategy for older individuals with cognitive decline.

中文翻译：

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动脉僵硬与以后生活中的执行功能障碍有关。

老年人的心血管疾病通常与认知障碍有关，尤其是在执行功能和处理速度方面。我们的目的是检查颈股脉搏波速度（PWV）是否与执行功能和处理速度的细微变化有关。对56名有主观情绪和/或认知问题的个体进行PWV和神经心理学评估，评估其处理速度（追踪测试A部分）和执行功能（Delis Kaplan执行功能系统Stroop任务；追踪测试B部分，TMT-B）。与低PWV（<12.0m / s）相比，高PWV（≥12.0m/ s）的人在TMT-B上的表现较差，并且PWV与PWV之间存在中等程度的负相关（r = -0.38，p = .004）。 TMT-B性能。我们的结果证实，在老年人中，认知能力下降的风险较大，