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Frontiers in Molecular Evolutionary Medicine.
Journal of Molecular Evolution ( IF 3.9 ) Pub Date : 2019-04-09 , DOI: 10.1007/s00239-019-09893-5
Stephen C Stearns 1
Affiliation  

This paper surveys some of the important insights that molecular evolution has contributed to evolutionary medicine; they include phage therapy, cancer biology, helminth manipulation of the host immune system, quality control of gametes, and pathogen outbreaks. Molecular evolution has helped to revolutionize our understanding of cancer, of autoimmune disease, and of the origin, spread, and pathogenesis of emerging diseases, where it has suggested new therapies, illuminated mechanisms, and revealed historical processes: all have practical therapeutic implications. While much has been accomplished, much remains to be done.

中文翻译:

分子进化医学前沿。

本文调查了分子进化对进化医学的重要贡献。它们包括噬菌体疗法,癌症生物学,蠕虫对宿主免疫系统的操纵,配子的质量控制和病原体爆发。分子进化帮助彻底改变了我们对癌症,自身免疫性疾病以及新兴疾病的起源,传播和发病机制的理解,在此方面人们提出了新的疗法,有启发性的机制并揭示了历史过程:所有这些都具有实际的治疗意义。尽管已完成许多工作,但仍有许多工作要做。
更新日期:2019-11-01
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