The functional unit in skeletal muscle is the multinucleated myofiber, which is composed of parallel arrays of microfibrils. The myofiber and sarco-mere structure of skeletal muscle are established during embryogenesis, when mononuclear myoblast cells fuse to form multinucleated myotubes and develop into muscle fibers. With the myoblasts permanently unable to enter a proliferative state again after they fuse to form the multinucleated myotube, postnatal myofiber growth, muscle homeostasis, and myofiber regeneration are dependent on a myogenic stem cell, the satellite cell. Because the satellite cell is a partially differentiated stem cell controlling the state of skeletal muscle structure throughout the life of the bird, it can impact muscle development and structure, growth, and regeneration and, subsequently, meat quality. When myofibers are damaged, muscle repair is dependent on the satellite cells. Regenerated myofibers after the repair process should be similar to the original muscle fiber. Despite significant improvements in meat-type birds, degenerative myopathies have arisen. In many of these degenerative breast muscle myopathies, like Wooden Breast, satellite cell-mediated regeneration of muscle is suppressed. Thus, the biological function of avian myogenic satellite cells and their influence on cellular mechanisms affecting breast muscle development and growth, function during degenerative myopathies, and meat quality are discussed.

中文翻译：

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与家禽生长有关的乳肌肌病的最新发展。

骨骼肌中的功能单元是多核肌纤维，它由微纤维的平行阵列组成。当单核成肌细胞融合形成多核肌管并发育成肌纤维时，胚胎形成过程中就建立了骨骼肌的肌纤维和肌节结构。由于成肌细胞在融合形成多核肌管后永久无法再次进入增生状态，因此产后肌纤维的生长，肌肉稳态和肌纤维再生取决于成肌干细胞，即卫星细胞。由于卫星细胞是在鸟类的整个生命过程中控制骨骼肌结构状态的部分分化的干细胞，因此它会影响肌肉的发育和结构，生长和再生，进而影响肉质。当肌纤维受损时，肌肉修复取决于卫星细胞。修复过程后的再生肌纤维应类似于原始的肌纤维。尽管肉类禽类有了显着改善，但发生了变性​​肌病。在许多这类退化性的胸部肌肉肌病中，例如木制乳房，卫星细胞介导的肌肉再生受到抑制。因此，讨论了禽肌原性卫星细胞的生物学功能及其对影响乳腺发育和生长的细胞机制的影响，变性肌病期间的功能以及肉质。退行性肌病已经出现。在许多这类退化性的胸部肌肉肌病中，例如木制乳房，卫星细胞介导的肌肉再生受到抑制。因此，讨论了禽肌原性卫星细胞的生物学功能及其对影响乳腺发育和生长的细胞机制的影响，变性肌病期间的功能以及肉质。退行性肌病已经出现。在许多这类退化性的胸部肌肉肌病中，例如木制乳房，卫星细胞介导的肌肉再生受到抑制。因此，讨论了禽肌原性卫星细胞的生物学功能及其对影响乳腺发育和生长的细胞机制的影响，变性肌病期间的功能以及肉质。