Two catalytic cascade cyclization methods (radical and 'cationic) to obtain aromatic polycyclic diterpenes hydroxylated at C3 starting from aromatic epoxypolyprenes were developed. The catalytic use of the Lewis superacid bismuth triflate produces a good yield of cyclized 2 from epoxypolyprene 3. This researchmay well direct future efforts to the synthesis of bioactive natural products.

中文翻译：

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芳族环氧无环戊二烯环化的研究：路易斯超强酸和二茂钛氯化物。

开发了两种催化级联环化方法（自由基和阳离子），以芳族环氧聚戊二烯为原料，在C3处羟基化得到芳族多环二萜。刘易斯超酸三氟甲基磺酸铋的催化用途可从环氧聚戊二烯3产生高产率的环化2。该研究可能将今后的工作直接引向生物活性天然产物的合成。