当前位置: X-MOL 学术Neuroscientist › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Postnatal Neural Stem Cells: Probing Their Competence for Cortical Repair.
The Neuroscientist ( IF 5.6 ) Pub Date : 2017-03-17 , DOI: 10.1177/1073858417697036
Vanessa Donega 1 , Olivier Raineteau 1
Affiliation  

There is growing evidence for a tentative cellular repair in the forebrain following perinatal injuries. In this review, we present the evidences and shortcomings in this regenerative attempt. We discuss recent progress in elucidating the origin, diversity, and competence of postnatal neural stem cells/progenitor cells. Finally, we propose new strategies to recruit postnatal progenitors to generate specific subtypes of cortical neurons or oligodendrocytes, thereby allowing the development of tailor-made approaches to treat perinatal brain injuries.

中文翻译:

产后神经干细胞:探究其皮质修复能力。

越来越多的证据表明围产期损伤后前脑细胞会暂时修复。在这篇综述中,我们提出了这种再生尝试的证据和不足。我们讨论在阐明出生后神经干细胞/祖细胞的起源,多样性和能力方面的最新进展。最后,我们提出了新的策略来招募产后祖细胞以生成特定的皮层神经元或少突胶质细胞亚型,从而允许开发量身定制的方法来治疗围产期脑损伤。
更新日期:2019-11-01
down
wechat
bug