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Bacterial Magnetosome: A Novel Biogenetic Magnetic Targeted Drug Carrier with Potential Multifunctions.
Journal of Nanomaterials ( IF 3.791 ) Pub Date : 2011-09-20 , DOI: 10.1155/2011/469031 Jianbo Sun 1 , Ying Li , Xing-Jie Liang , Paul C Wang
Journal of Nanomaterials ( IF 3.791 ) Pub Date : 2011-09-20 , DOI: 10.1155/2011/469031 Jianbo Sun 1 , Ying Li , Xing-Jie Liang , Paul C Wang
Affiliation
Bacterial magnetosomes (BMs) synthesized by magnetotactic bacteria have recently drawn great interest due to their unique features. BMs are used experimentally as carriers for antibodies, enzymes, ligands, nucleic acids, and chemotherapeutic drugs. In addition to the common attractive properties of magnetic carriers, BMs also show superiority as targeting nanoscale drug carriers, which is hardly matched by artificial magnetic particles. We are presenting the potential applications of BMs as drug carriers by introducing the drug-loading methods and strategies and the recent research progress of BMs which has contributed to the application of BMs as drug carriers.
中文翻译:
细菌磁小体:一种具有潜在多功能的新型生物遗传磁性靶向药物载体。
由趋磁细菌合成的细菌磁小体(BMs)由于其独特的特性最近引起了极大的兴趣。BM 在实验中用作抗体、酶、配体、核酸和化疗药物的载体。除了磁性载体的共同吸引力外,BMs还表现出作为靶向纳米级药物载体的优势,这是人工磁性颗粒难以匹敌的。我们介绍了BMs作为药物载体的潜在应用,介绍了载药方法和策略以及BMs最近的研究进展,这些进展对BMs作为药物载体的应用做出了贡献。
更新日期:2011-09-20
中文翻译:
细菌磁小体:一种具有潜在多功能的新型生物遗传磁性靶向药物载体。
由趋磁细菌合成的细菌磁小体(BMs)由于其独特的特性最近引起了极大的兴趣。BM 在实验中用作抗体、酶、配体、核酸和化疗药物的载体。除了磁性载体的共同吸引力外,BMs还表现出作为靶向纳米级药物载体的优势,这是人工磁性颗粒难以匹敌的。我们介绍了BMs作为药物载体的潜在应用,介绍了载药方法和策略以及BMs最近的研究进展,这些进展对BMs作为药物载体的应用做出了贡献。