One aspect of smoking and lung cancer that has not been closely examined, is that regarding genes that may predispose to tobacco dependence. Smoking and mental illness are tightly linked, apparently the result of smokers using cigarettes to self-medicate for mental problems. The gene for solute carrier family 18 member A1 (vesicular monoamine transporter; SLC18A1) is of particular interest in this regard because of its association with schizophrenia, autism and bipolar illness as well as with cancer. In the current study, the relationship of SLC18A1 expression with smoking and lung cancer was analyzed.

中文翻译：

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囊泡单胺转运蛋白基因溶出载体家族18成员1（SLC18A1）在肺癌中的表达。

尚未仔细研究的吸烟和肺癌的一个方面是关于可能易患烟草依赖的基因。吸烟与精神疾病有着密切的联系，这显然是吸烟者使用香烟对精神问题进行自我药物治疗的结果。在这方面，溶质载体家族18成员A1（水泡单胺转运蛋白； SLC18A1）的基因特别受关注，因为它与精神分裂症，自闭症和躁郁症以及癌症相关。在本研究中，分析了SLC18A1表达与吸烟和肺癌的关系。