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Advancing berry research in cancer
Journal of Berry Research ( IF 1.7 ) Pub Date : 2018-12-20 , DOI: 10.3233/jbr-189001
Pan Pan 1 , Li-Shu Wang 1
Affiliation  

Cancer is the second leading cause of death worldwide, having caused 8.8 million deaths in 2015. That is nearly 1 in 6 of all global deaths. Around one third of deaths from cancer are due to the 5 leading behavioral and dietary risks: high body mass index, low fruit and vegetable intake, lack of physical activity, tobacco use, and alcohol use. Berries include many commonly consumed fruits and vegetables, such as strawberries, blueberries, blackberries, red raspberries, black raspberries, cranberries, grape, kiwi, banana, tomatoes, eggplant, cucumber, watermelon, etc., as well as many uncommon types, such as gooseberries, Goji berries, elderberries, noni (Morinda citrifolia), and acai (Euterpe oleracea Mart), etc. Berries are known to contain abundant phytochemicals and natural bioactive compounds, which have been reported as anti-cancer agents. Therefore, the beneficial effects and the underlying mechanisms of berries against cancers are important topics in cancer research. Articles in this special issue reported the recent advances of berry research in cancers including human efficacy trials and the use of animal models and cell culture systems to elucidate mechanisms of action. The topics include, but are not limited to, strategies to enhance bioavailability of berry phytochemicals for cancer therapeutics, the role of gut bacteria in berry-mediated cancer prevention, anti-inflammation as the major anti-cancer mechanism using berries, berries’ effects on H. pylori and gastric cancer, etc. Overall, the findings not only support the use of berries to reduce cancer risk but also explore the potential use of berry phytochemicals for cancer therapeutics.

中文翻译:

推进浆果在癌症中的研究

癌症是全球第二大死因,2015 年造成 880 万人死亡。这几乎占全球死亡人数的六分之一。大约三分之一的癌症死亡是由于 5 种主要的行为和饮食风险造成的:高体重指数、低水果和蔬菜摄入量、缺乏体育锻炼、吸烟和饮酒。浆果包括许多经常食用的水果和蔬菜,如草莓、蓝莓、黑莓、红树莓、黑树莓、蔓越莓、葡萄、猕猴桃、香蕉、西红柿、茄子、黄瓜、西瓜等,以及许多不常见的类型,如如醋栗、枸杞、接骨木、诺丽 (Morinda citrifolia) 和巴西莓 (Euterpe oleracea Mart) 等。众所周知,浆果含有丰富的植物化学物质和天然生物活性化合物,已被报道为抗癌剂。因此,浆果抗癌的有益作用和潜在机制是癌症研究的重要课题。本期特刊中的文章报道了浆果癌症研究的最新进展,包括人体功效试验以及使用动物模型和细胞培养系统阐明作用机制。主题包括但不限于提高用于癌症治疗的浆果植物化学物质的生物利用度的策略、肠道细菌在浆果介导的癌症预防中的作用、抗炎作为使用浆果的主要抗癌机制、浆果对癌症的影响H. pylori 和胃癌等。总体而言,这些发现不仅支持使用浆果降低癌症风险,还探索了浆果植物化学物质在癌症治疗中的潜在用途。浆果抗癌的有益作用和潜在机制是癌症研究的重要课题。本期特刊中的文章报道了浆果癌症研究的最新进展,包括人体功效试验以及使用动物模型和细胞培养系统阐明作用机制。主题包括但不限于提高用于癌症治疗的浆果植物化学物质的生物利用度的策略、肠道细菌在浆果介导的癌症预防中的作用、抗炎作为使用浆果的主要抗癌机制、浆果对癌症的影响H. pylori 和胃癌等。总体而言,这些发现不仅支持使用浆果降低癌症风险,还探索了浆果植物化学物质在癌症治疗中的潜在用途。浆果抗癌的有益作用和潜在机制是癌症研究的重要课题。本期特刊中的文章报道了浆果癌症研究的最新进展,包括人体功效试验以及使用动物模型和细胞培养系统阐明作用机制。主题包括但不限于提高用于癌症治疗的浆果植物化学物质的生物利用度的策略、肠道细菌在浆果介导的癌症预防中的作用、抗炎作为使用浆果的主要抗癌机制、浆果对癌症的影响H. pylori 和胃癌等。总体而言,这些发现不仅支持使用浆果降低癌症风险,还探索了浆果植物化学物质在癌症治疗中的潜在用途。
更新日期:2018-12-20
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