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The application of titanium dioxide, zinc oxide, fullerene, and graphene nanoparticles in photodynamic therapy.
Cancer Nanotechnology ( IF 5.7 ) Pub Date : 2017-10-19 , DOI: 10.1186/s12645-017-0032-2
Zahraa Youssef 1 , Régis Vanderesse 2 , Ludovic Colombeau 1 , Francis Baros 1 , Thibault Roques-Carmes 1 , Céline Frochot 1 , Habibah Wahab 3 , Joumana Toufaily 4 , Tayssir Hamieh 4 , Samir Acherar 2 , Amirah Mohd Gazzali 2, 3
Affiliation  

Nanoparticles (NPs) have been shown to have good ability to improve the targeting and delivery of therapeutics. In the field of photodynamic therapy (PDT), this targeting advantage of NPs could help ensure drug delivery at specific sites. Among the commonly reported NPs for PDT applications, NPs from zinc oxide, titanium dioxide, and fullerene are commonly reported. In addition, graphene has also been reported to be used as NPs albeit being relatively new to this field. In this context, the present review is organized by these different NPs and contains numerous research works related to PDT applications. The effectiveness of these NPs for PDT is discussed in detail by collecting all essential information described in the literature. The information thus assembled could be useful in designing new NPs specific for PDT and/or PTT applications in the future.

中文翻译:

二氧化钛,氧化锌,富勒烯和石墨烯纳米颗粒在光动力治疗中的应用。

纳米粒子(NPs)已显示具有改善治疗剂靶向和递送的良好能力。在光动力疗法(PDT)领域,NP的这种靶向优势可以帮助确保药物在特定部位的递送。在用于PDT的通常报道的NP中,来自氧化锌,二氧化钛和富勒烯的NP被普遍报道。此外,尽管石墨烯在该领域相对较新,但据报道也被用作NP。在这种情况下,本综述由这些不同的NP组织,并包含许多与PDT应用相关的研究工作。通过收集文献中描述的所有基本信息,详细讨论了这些NP对PDT的有效性。
更新日期:2017-10-19
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