Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) interacts with CDK2AP2, modulates the actions of transforming growth factor-B1, cyclin-dependent kinase 2 and retinoblastoma protein, and closely interacts with micro-RNA21 and micro-RNA25. Our objective was to determine if CDK2AP1 mRNA expression levels were consistent with tumour-suppressive functions in breast cancer.

中文翻译：

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CDK2AP1 mRNA在人乳腺癌中的表达：与临床和病理参数的关系。

细胞周期蛋白依赖性激酶2相关蛋白1（CDK2AP1）与CDK2AP2相互作用，调节转化生长因子B1，细胞周期蛋白依赖性激酶2和成视网膜细胞瘤蛋白的作用，并与microRNA21和microRNA25紧密相互作用。我们的目标是确定CDK2AP1 mRNA表达水平是否与乳腺癌中的肿瘤抑制功能一致。