当前位置: X-MOL 学术Cancer Genom. Proteom. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
MGMT Gene Promoter Methylation Status - Assessment of Two Pyrosequencing Kits and Three Methylation-specific PCR Methods for their Predictive Capacity in Glioblastomas.
Cancer Genomics & Proteomics ( IF 2.5 ) Pub Date : 2018-10-22 , DOI: 10.21873/cgp.20102
Lene E Johannessen 1 , Petter Brandal 1, 2 , Tor Åge Myklebust 3, 4 , Sverre Heim 1, 5 , Francesca Micci 1 , Ioannis Panagopoulos 6
Affiliation  

Although methylation of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter predicts response to temozolomide in patients with glioblastoma, no consensus exists as to which assay is best for its detection.

中文翻译:

MGMT基因启动子甲基化状态-评估两种胶体测序试剂盒和三种甲基化特异性PCR方法对胶质母细胞瘤的预测能力。

尽管O 6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)基因启动子的甲基化可预测成胶质母细胞瘤患者对替莫唑胺的反应,但对于哪种检测最适合其检测尚无共识。
更新日期:2020-08-21
down
wechat
bug